Molecular docking studies of forty two compounds taken from literature were carried out against COX-II molecular target using Molegro Virtual Docker v 4.0.2 to accomplish preliminary confirmation of the observed in-vivo anti inflammatory activity. Docking studies have shown that the title compound interact and bind efficiently with 1CX2 subunits of Cyclo oxygenase enzyme which resulted in anti inflammatory activity. The quantitative assessment after docking procedure was made on the basis of Mol dock scores, hydrogen bond. Almost all the compounds showed higher mol dock score in comparison to reference or coexisting drug in receptor ICX2.
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